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women,
pregnancy.
Melanocytes
are the cells in the epidermis which produce melanin. They
deliver melanin through dendrites, which are octopus like arms
that connect to surrounding keratinocytes. Melanocytes respond
to sunlight by producing more melanin and more melanocytes.
This is to protect the keratinocytes, one of the main reasons
for melanin production. Melanosomes, which are a
particle of melanin, form a shield over the nucleus of the
living keratinocyte cells to prevent solar radiation damage.
Keep
in mind that tanning is a protective mechanism, not a
therapeutic mechanism, and that it is designed to help protect
us against excessive solar radiation.
Long term the effects of solar radiation will cause pigment to
pool from leaking melanocytes. This is seen as "age
spots". In this case, the melanocyte has been damaged by
UV exposure and needs to be repaired.
Hyperpigmentation
in pregnancy occurs in about 90% of women. Blotchy
hyperpigmentation on the face, called Melasma happens
in about 70% of pregnant women. This is most likely due to
hormonal changes that are aggravated by sun exposure.
HOW TO REDUCE SKIN HYPERPIGMENTATION?
The
spots and blemishes removal
To
understand the possible treatments for hyperpigmentation it is
necessary to understand a little about one of the enzymes that
are responsible for melanin production. This enzyme is called Tyrosinase.
Tyrosinase determines just how much melanin is produced. The
majority of products available to treat hyperpigmentation
inhibit tyrosinase. Tyrosinase inhibitors by reducing activity
of the tyrosinase diminishes amount of melanine produced. In
practice it can be seen as a skin whitening, diminishing the
intensity or complete removal of the spots and blemishes.
NATURAL
ANTI-SPOTS AND BLEMISHES CREAM CONTAINS:
Active
ingredients:
-
Mulberry root extract(Morus
alba) , natural tyrosinase inhibitor, with the
active
constituent:
2,3',4,5'-tetrahydroxystilbene
2-oxyresveratrol.
-
Bearberry leaf extract(Arctostaphylos
uva ursi), natural tyrosinase inhibitor with the
active constituent:
arbutin.
-
Combava
essential oil
(Citrus hystrix),
-
Zinc oxide, Titanium dioxide.
Other
ingredients:
-
Talc, Lanoline, Vaseline, Bee wax, Almond oil, Glycerine,
Propylene glycol, Vitamin E.
MECHANISM OF ACTION:
Natural Anti-Spots and Blemishes cream, contains tyrosinase inhibitors ,
as an active ingredients of the mulberry root
(Morus
alba),
and bearberry leaf (Arctostaphylos
uva ursi) extracts, which acting on tha basis of synergy and by the
competitive way, diminish of the tyrosinase activity, and thus a melanine
production, which lead to the final skin whitening and spots and blemishes
removal.
The combava
essential oil (Citrus hystrix)
acts as a natural detergent, removing of the surface layer of the dead
cells containing of the surplus of melanine, making possible of the faster
renewal of the new young cells containing a less melanine.
Zinc oxide and
Titanium dioxide form a physical barrier to the sunrays in the range from
290 nm to 700 nm, and in the natural way protect the skin from the harmful
effects of the UVA and UVB radiation. This is especially important because
by losing the melanine as a sun protector, skin becomes a more vulnerable
to the harmful effects of the UVA and UVB radiation.
THE WAY OF
APPLICATION:
Twice a day in the morning and in the evening, apply
the cream on the area of the spots and blemishes and rub firmly.
Make sure that cream has absorbed well.
The first sign of whitening usually appears after 5 to 7 days from the
start of application, and full effect achieves for 12 to 15 days.
CONTRAINDICATIONS:
Not known.
UNDESIRABLE
EFFECTS: Not
known.
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